Health is among the key areas of prime concern among most people. With the advent of the discipline of medicine, health has been improved a great deal. Extensive research has been conducted in the past, and is still an ongoing process, in a bid to curb and eliminate all sorts of health problems. Among the recent breakthroughs is concerned with liposomal formulation.
There has always existed the problem of ingested drugs being digested before reaching their intended target areas in the body. The process of these formulations was discovered as scientists were looking for a solution to this problem. In this solution, the drug would be closed in and protected by a layer of phospholipids and aqueous solution.
Liposomes bio structure is favorable. They are mainly aqueous at the core. This is close in by a layer of phospholipids. Various strains have different types of phospholipids they could be either natural or synthetically prepared in a laboratory. This provides an ideal state where both extremes of drugs can be safely transported, by either attaching to the liquid core or the lipid outer layers.
The core structure of liposomes is what causes them to be preferred among researchers of various fields and disciplines. They are formed when phospolipids are immersed in water and a specific amount of heat directed toward them. To determine if it is an appropriate carrier for a given drug, the chemical composition should be bench-marked against that of the drug, so as to avert reactions.
When such discoveries are made, researchers are eager to push it so as to find out if the new discovery can lead to better drugs. IN this case it did. An anthracycline drug known as Doxorubicin was developed to help control the spread of cancer. This is achieved by injecting stains of base DNA and RNA into the malignant cells. The enzyme topoisomerase is also injected at a later stage. These procedures inhibit replication of the cells actively controlling their growth.
It is due to advances in the medical field that control of many diseases is not a reality. Terminal illnesses previously viewed as a death sentence are now controllable and some even treatable. Research on cancer and liposomes has led to development of anti-cancer drugs an their carriers. The development has brought about continuing tests and usage of doxorubicin, paclitaxel, cisplatin, lipoplatin, aroplatin among others.
The study of liposomes has also led to development of vaccines and various other treatments. Various diseases and medical conditions which previously had no cure can now be vaccinated against. Such developments have established Epaxal, a vaccine against Hepatitis A, and Inflexal V, a vaccine against several types of influenza. A vaccine known as Stimuvax against lighter forms of cancer is in the offing.
The formulation is being investigated on how well it will serve in transportation of dietary supplements to various parts of the body. This testing is inspired by the exceptional success in performance of liposomes in targeted drug delivery. If successful, scientists will use liposomes to transport supplements to various parts of the body where they are required by the body. This procedure has been tried and worked. Therefore, its no longer a risk.
There has always existed the problem of ingested drugs being digested before reaching their intended target areas in the body. The process of these formulations was discovered as scientists were looking for a solution to this problem. In this solution, the drug would be closed in and protected by a layer of phospholipids and aqueous solution.
Liposomes bio structure is favorable. They are mainly aqueous at the core. This is close in by a layer of phospholipids. Various strains have different types of phospholipids they could be either natural or synthetically prepared in a laboratory. This provides an ideal state where both extremes of drugs can be safely transported, by either attaching to the liquid core or the lipid outer layers.
The core structure of liposomes is what causes them to be preferred among researchers of various fields and disciplines. They are formed when phospolipids are immersed in water and a specific amount of heat directed toward them. To determine if it is an appropriate carrier for a given drug, the chemical composition should be bench-marked against that of the drug, so as to avert reactions.
When such discoveries are made, researchers are eager to push it so as to find out if the new discovery can lead to better drugs. IN this case it did. An anthracycline drug known as Doxorubicin was developed to help control the spread of cancer. This is achieved by injecting stains of base DNA and RNA into the malignant cells. The enzyme topoisomerase is also injected at a later stage. These procedures inhibit replication of the cells actively controlling their growth.
It is due to advances in the medical field that control of many diseases is not a reality. Terminal illnesses previously viewed as a death sentence are now controllable and some even treatable. Research on cancer and liposomes has led to development of anti-cancer drugs an their carriers. The development has brought about continuing tests and usage of doxorubicin, paclitaxel, cisplatin, lipoplatin, aroplatin among others.
The study of liposomes has also led to development of vaccines and various other treatments. Various diseases and medical conditions which previously had no cure can now be vaccinated against. Such developments have established Epaxal, a vaccine against Hepatitis A, and Inflexal V, a vaccine against several types of influenza. A vaccine known as Stimuvax against lighter forms of cancer is in the offing.
The formulation is being investigated on how well it will serve in transportation of dietary supplements to various parts of the body. This testing is inspired by the exceptional success in performance of liposomes in targeted drug delivery. If successful, scientists will use liposomes to transport supplements to various parts of the body where they are required by the body. This procedure has been tried and worked. Therefore, its no longer a risk.
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